Sleep architecture and recovery
Sermorelin + DSIP — natural GH and slow-wave sleep promotion.
About this protocol
A sleep-focused pair that addresses the sleep–GH feedback loop. Sermorelin stimulates pituitary GH release through natural feedback mechanisms; DSIP supports slow-wave sleep architecture — the stage where the deepest GH pulses and physical recovery occur.
Who it's for: Adults with documented or self-reported sleep disruption, fragmented sleep, or recovery deficits.
What's in this protocol
DEEP REST pairs 2 compounds:
Sermorelin
Growth Hormone-Releasing Hormone analog
Synthetic analog of the first 29 amino acids of human GHRH. Stimulates the pituitary to release GH in a physiological, pulsatile manner that follows natural circadian rhythms — most effective during slow-wave sleep.
Used for
DSIP
Delta Sleep-Inducing Peptide
Naturally occurring neuropeptide originally isolated from rabbit thalamus in 1974. Modulates serotonergic, GABAergic, and opioid systems to promote slow-wave sleep stages — those most critical for physical recovery and nocturnal GH release.
Used for
What members are working toward
The following reflects areas of interest commonly reported by members and studied in the clinical literature. Results depend on individual health status, labs, and physician-directed care. Nothing below constitutes a treatment claim.
Slow-wave sleep promotion
DSIP is named for its observed effect on delta-stage sleep — the recovery-rich phase of sleep architecture that thins with age and chronic stress.
Sleep onset and continuity
Members commonly report shorter sleep latency and reduced fragmentation within weeks — particularly during high-stress periods or after travel.
Physical recovery
Most natural GH secretion occurs during slow-wave sleep. Supporting both the sleep stage and the GH axis directly amplifies overnight tissue and metabolic repair.
Cognitive and mood support
Sleep architecture is upstream of focus, mood, and cognitive resilience. DEEP REST is a foundational protocol for members whose cognitive issues trace back to sleep.
Relevant bloodwork markers
DEEP REST is prescribed and monitored against bloodwork. The Halftime Baseline panel ($249, separate onboarding deliverable) covers the relevant markers below.
Aligned intents
DEEP REST is most commonly chosen by members whose primary intent is one of:
How to subscribe
Available at every tier
- Foundation $199/mo — pick DEEP REST as your 1 protocol
- Optimizer $349/mo — pair DEEP REST with 1 other protocol
- Elite $549/mo — stack DEEP REST with 2 other protocols
Premium add-ons (VITALIZE, IMMUNE GUARD, MITOCORE) bill separately on top of any tier. The Halftime Baseline bloodwork panel ($249) is a separate onboarding deliverable, available at any tier.
Join the waitlistLaunching July 1, 2026
All prescriptions require physician evaluation. Compounded medications are not FDA-approved. Individual results vary. This is not medical advice.