Mitochondrial & metabolic activation
MOTS-c — mitochondrial and metabolic activation.
- HIPAA-Compliant
- US-Licensed Physicians
- PCAB-Accredited Compounding
- Available in 46 States
- Telehealth-Compliant
About this protocol
A metabolic protocol built around MOTS-c, a mitochondrial-derived peptide that acts as an exercise mimetic — supporting insulin sensitivity, metabolic flexibility, and mitochondrial function.
Who it's for: Adults focused on metabolic health, insulin sensitivity, and cellular energy.
What's in this protocol
MITOCORE is built around a single compound:
MOTS-c
MOTS-c (mitochondrial-derived peptide)
Peptide encoded by mitochondrial DNA that acts as a mitokine — a metabolic signaling molecule. Research suggests exercise-mimetic effects, improved insulin sensitivity, and support for mitochondrial biogenesis.
Used for
What members are working toward
The following reflects areas of interest commonly reported by members and studied in the clinical literature. Results depend on individual health status, labs, and physician-directed care. Nothing below constitutes a treatment claim.
Mitochondrial activation
MOTS-c signals at the mitochondrial level, supporting the energy-producing machinery that declines with age.
Metabolic flexibility
Research suggests improved insulin sensitivity and metabolic adaptability — relevant for adults managing metabolic health.
Exercise-mimetic effects
MOTS-c mimics some signaling effects of exercise, complementing training rather than replacing it.
Relevant labs markers
MITOCORE is prescribed and monitored against labs. The Halftime Baseline panel ($249, separate onboarding deliverable) covers the relevant markers below.
Aligned intents
MITOCORE is most commonly chosen by members whose primary intent is one of:
How to subscribe
Available at every tier
- Foundation $199/mo — pick MITOCORE as your 1 protocol
- Optimizer $349/mo — pair MITOCORE with 1 other protocol
- Elite $549/mo — stack MITOCORE with 2 other protocols
The Halftime Baseline lab panel ($249) is a separate onboarding deliverable, available at any tier.
Join the waitlistLaunching July 1, 2026
All prescriptions require physician evaluation. Compounded medications are not FDA-approved. Individual results vary. This is not medical advice.