Cognitive focus and stress modulation
Semax + Selank — BDNF elevation and anxiolytic clarity, intranasal.
About this protocol
A nasally-delivered two-peptide stack that supports cognitive performance through complementary mechanisms — Semax elevates BDNF and supports neuroprotection; Selank provides anxiolytic clarity without the dependency or sedation profile of benzodiazepines. Intranasal delivery achieves rapid CNS access.
Who it's for: Adults navigating high cognitive load, midlife cognitive changes, or chronic stress — looking for tools beyond stimulants.
What's in this protocol
SHARP MIND pairs 2 compounds:
Semax
Semax (ACTH 4-7 Pro-Gly-Pro heptapeptide)
Synthetic heptapeptide developed at the Institute of Molecular Genetics, Russian Academy of Sciences. Increases BDNF (brain-derived neurotrophic factor), enhances dopaminergic and serotonergic neurotransmission, provides neuroprotection against oxidative and ischemic stress.
Used for
Selank
Selank (tuftsin analog heptapeptide)
Synthetic tuftsin analog that produces anxiolytic effects through GABAergic and serotonergic pathways — without the dependency, tolerance, or cognitive dulling associated with benzodiazepines.
Used for
What members are working toward
The following reflects areas of interest commonly reported by members and studied in the clinical literature. Results depend on individual health status, labs, and physician-directed care. Nothing below constitutes a treatment claim.
Focus and working memory
Semax has been studied for working memory, focus, and BDNF elevation — neurotrophic factors that support the neuroplasticity behind sustained attention.
Anxiolytic clarity
Selank produces anxiety reduction without sedation, tolerance, or dependency — distinct from benzodiazepines, suitable for daily use.
Neuroprotection
Both peptides have been studied for neuroprotective effects against oxidative stress — relevant in the context of long-term cognitive health.
Rapid CNS access
Intranasal delivery bypasses the first-pass metabolism limitations that affect oral cognitive support — a meaningful pharmacokinetic advantage for neuropeptides.
Relevant bloodwork markers
SHARP MIND is prescribed and monitored against bloodwork. The Halftime Baseline panel ($249, separate onboarding deliverable) covers the relevant markers below.
Aligned intents
SHARP MIND is most commonly chosen by members whose primary intent is one of:
How to subscribe
Available at every tier
- Foundation $199/mo — pick SHARP MIND as your 1 protocol
- Optimizer $349/mo — pair SHARP MIND with 1 other protocol
- Elite $549/mo — stack SHARP MIND with 2 other protocols
Premium add-ons (VITALIZE, IMMUNE GUARD, MITOCORE) bill separately on top of any tier. The Halftime Baseline bloodwork panel ($249) is a separate onboarding deliverable, available at any tier.
Join the waitlistLaunching July 1, 2026
All prescriptions require physician evaluation. Compounded medications are not FDA-approved. Individual results vary. This is not medical advice.